Enhanced HIV-1 Replication in CD4+ T Cells Derived from Individuals with Latent Mycobacterium tuberculosis Infection.

Mycobacterium tuberculosis (Mtb) and HIV co-infection increases mortality, accelerating progression to AIDS and worsen the disease tuberculosis. However, the impact of existing Mtb infection in subsequent HIV infection has not been fully explored.

We hypothesize that Mtb infection immunology create an environment that affect course of HIV infection and to investigate whether there was an impact Mtb infection of CD4 + T cell susceptibility to HIV-1 infection.Plasma and CD4 + T cells isolated from the blood of HIV-negative spectrum Mtb infection and individual control of non-Mtb-infected analyzed for markers of inflammation and cell phenotype T cell CD4 + T-cells infected with HIV-1 in vitro and monitored for viral replication.

We observable differences in pro-inflammatory cytokines and the relative proportion of a memory T cell subsets depending on the status of Mtb infection. Cells CD4 + T-cells derived from individuals with latent Mtb infection is supported by more efficient HIV-1 transcription, release, and replication. Enhanced HIV-1 replication correlated with a higher percentage of CD4 + TEM and TTD-existing cells.Pre Mtb infection immunology create an environment that reflects the status of Mtb infection and the effect of CD4 + T cell susceptibility to HIV-1 replication. These findings provide insight into the cellular and molecular how there Mtb infection with HIV-1 pathogenesis influence.

100 BP DNA LADDER, 500UL PER KIT

M-DNA-100BP 1/pk
EUR 73
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT

M-DNA-1KB 1/pk
EUR 70
Description: Bioscience Mol Bio; DNA Ladder

DNA Gyrase Assay Kit

TG1003 100 assays
EUR 313

QuantiFluo DNA Assay Kit

QFDN-250 250
EUR 351
Description: Quantitative determination of DNA by fluorimetric (340nm/450nm) method. Procedure: 5 min. Kit size: 250 tests. Detection limit: 100 ng/mL. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

ApoBrdU DNA Fragmentation Assay Kit

55R-1396 60 assays
EUR 1083
Description: DNA Fragmentation Assay Kit for use in the research laboratory

ApoDIRECT DNA Fragmentation Assay Kit

55R-1397 50 assays
EUR 1086
Description: DNA Fragmentation Assay Kit for use in the research laboratory

DNA Quantification Assay Kit (Fluorometric)

K539-200
EUR 262

DNA Quantification Assay Kit (Fluorometric)

K539-2000
EUR 392

ApoBrdU DNA Fragmentation Assay Kit

K2070-60 60 assays
EUR 766

ApoDIRECT DNA Fragmentation Assay Kit

K2071-50 50 assays
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ApoBrdU DNA Fragmentation Assay Kit

K401-60
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ApoDIRECT DNA Fragmentation Assay Kit

K402-50
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ApoBrdU-IHC DNA Fragmentation Assay Kit

55R-1398 50 assays
EUR 1086
Description: DNA Fragmentation Assay Kit for use in the research laboratory

ApoBrdU-IHC DNA Fragmentation Assay Kit

K2072-50 50 assays
EUR 835

ApoBrdU-IHC DNA Fragmentation Assay Kit

K403-50
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EpiQuik In Situ DNA Damage Assay Kit

P-6001 2x96 assays
EUR 1034.55
Description: kits suitable for this type of research

EpiQuik DNA Demethylase Activity/Inhibition Assay Kit

P-3019 96 Assays
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Description: The best epigenetics products

Human TDP1 Assay Kit (DNA/Top1 Complex)

TG1004-1A 100 assays
EUR 560

Human TDP1 Assay Kit (DNA/Top1 Complex)

TG1004-2A 250 assays
EUR 660

Topoisomerase I Assay Kit (25ug SC DNA)

TG1015-1 100 assays
EUR 302

Topoisomerase I Assay Kit (62.5ug SC DNA)

TG1015-2 250 assays
EUR 414

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase)

TG2000G-1KIT 100 assays
EUR 380

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase)

TG2000G-3KIT 500 assays
EUR 985

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase)

TG2000G-5KIT 1000 assays
EUR 1612

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase)

TG2000G-7KIT 2000 assays
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EvaEZ Flurometric DNA Polymerase Activity Assay (200 rxn)

29051 2mL
EUR 459
Description: Minimum order quantity: 1 unit of 2mL

HIF-1 Alpha DNA Binding Activity Assay Kit

CBA-282 96 assays
EUR 635
Description: Cell Biolabs? HIF-1 Alpha DNA Binding Activity Assay Kit is an immunoassay developed for rapid detection of activated HIF-1 in any protein sample. Active HIF-1 complex is captured on a double stranded oligonucleotide containing an HRE that is attached to the well. HIF-1 Alpha is then detected with an anti-HIF-1 Alpha antibody followed by an HRP conjugated secondary antibody. Each kit provides sufficient reagents to perform up to a total of 96 assays, and can detect HIF-1 Alpha from human, mouse, or rat. The HIF-1 DNA Binding Activity Assay takes only 4.5 hours to complete compared to a standard 3 day electromobility shift (EMSA) method.

EpiQuik General Protein-DNA Binding Assay Kit (Colorimetric)

P-2004 96 Assays
EUR 614.05
Description: kits suitable for this type of research

EpiQuik General Protein-DNA Binding Assay Kit (Fluorometric)

P-2005 96 Assays
EUR 628.55
Description: Ask the seller for details

EpiQuik DNA Methyltransferase (DNMT) Activity/Inhibition Assay Kit

P-3001 96 Assays
EUR 875.05
Description: fast delivery possible

EpiQuik DNA Demethylase Activity/Inhibition Assay Ultra Kit

P-3008 96 Assays
EUR 860.55
Description: Ask the seller for details

EZClick? TUNEL ? in situ DNA Fragmentation/Apoptosis Assay Kit

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EUR 533

EpiQuik DNA Methyltransferase (DNMT) Activity/Inhibition Assay Kit (Fluorometric)

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Description: The best epigenetics products

Epigenase Thymine DNA Glycosylase (TDG) Activity/Inhibition Assay Kit (Colorimetric)

P-3094 96 Assays
EUR 904.05
Description: fast delivery possible

Topoisomerase I Assay Kit (25ug SC DNA +100u Human Topo I)

TG1015-1A 100 assays
EUR 403

Topoisomerase I Assay Kit (62.5ug SC DNA + 250u Human Topo I)

TG1015-2A 250 assays
EUR 660

Topoisomerase I Assay Kit (125ug SC DNA + 500u Human Topo I)

TG1015-3A 500 assays
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XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)

30007 1KIT
EUR 236
Description: Minimum order quantity: 1 unit of 1KIT

Endothelial Tube Formation Assay (In Vitro Angiogenesis Assay)

CBA-200 50 assays
EUR 560
Description: For angiogenesis to occur, endothelial cells must escape their stable location and break through the basement membrane. Cells migrate toward an angiogenic stimulus that may be released from nearby tumor cells. These cells proliferate to form new blood vessels. Our Endothelial Tube Formation Assay (In Vitro Angiogenesis) provides an easy, robust system to assess angiogenesis in vitro. The ECM gel matrix very closely resembles an in vivo environment.

Glycosaminoglycans Assay Kit

6022 1 kit
EUR 419.75
Description: Glycosaminoglycans Assay Kit

Hemoglobin Assay Kit

6024 1 kit
EUR 180.5
Description: Hemoglobin Assay Kit

Proteasome Assay Kit

55R-1341 100 assays
EUR 654
Description: Assay Kit for detection of Proteasome in the research laboratory

Calpain Assay Kit

55R-1342 100 assays
EUR 779
Description: Assay Kit for detection of Calpain in the research laboratory

Glutathione Assay Kit

55R-1343 100 assays
EUR 654
Description: Assay Kit for detection of Glutathione in the research laboratory

Glutathione Assay Kit

55R-1354 100 assays
EUR 895
Description: Assay Kit for detection of Glutathione activity in the research laboratory

HDAC Assay Kit

55R-1371 100 assays
EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HDAC Assay Kit

55R-1372 100 assays
EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HAT Assay Kit

55R-1373 100 assays
EUR 740
Description: Assay Kit for detection of HAT in the research laboratory

SOD Assay Kit

55R-1374 100 assays
EUR 602
Description: Assay Kit for detection of SOD in the research laboratory

HDAC3 Assay Kit

55R-1377 100 assays
EUR 693
Description: Assay Kit for detection of HDAC3 in the research laboratory

HDAC8 Assay Kit

55R-1379 100 assays
EUR 689
Description: Assay Kit for detection of HDAC8 in the research laboratory

ATP Assay Kit

55R-1380 100 assays
EUR 809
Description: Assay Kit for detection of ATP in the research laboratory

ADP Assay Kit

55R-1381 100 assays
EUR 809
Description: Assay Kit for detection of ADP in the research laboratory

FAD Assay Kit

55R-1382 100 assays
EUR 732
Description: Assay Kit for detection of FAD in the research laboratory

PEP Assay Kit

55R-1384 100 assays
EUR 876
Description: Assay Kit for detection of PEP in the research laboratory

Ammonia Assay Kit

55R-1388 100 assays
EUR 740
Description: Assay Kit for detection of Ammonia in the research laboratory

cAMP Assay Kit

55R-1389 100 assays
EUR 706
Description: Assay Kit for detection of cAMP activity in the research laboratory

cGMP Assay Kit

55R-1390 100 assays
EUR 706
Description: Assay Kit for detection of cGMP activity in the research laboratory

Urea Assay Kit

55R-1391 100 assays
EUR 740
Description: Assay Kit for detection of Urea in the research laboratory

Calcium Assay Kit

55R-1392 250 assays
EUR 586
Description: Assay Kit for detection of Calcium activity in the research laboratory

Magnesium Assay Kit

55R-1393 100 assays
EUR 654
Description: Assay Kit for detection of Magnesium in the research laboratory

Zinc Assay Kit

55R-1394 100 assays
EUR 673
Description: Assay Kit for detection of Zinc in the research laboratory

Iron Assay Kit

55R-1395 100 assays
EUR 758
Description: Assay Kit for detection of Iron in the research laboratory

Phosphate Assay Kit

55R-1400 500 assays
EUR 415
Description: Assay Kit for detection of Phosphate in the research laboratory

JNK Assay Kit

55R-1407 40 assays
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Description: Assay Kit for detection of JNK in the research laboratory

JNK Assay Kit

55R-1408 40 assays
EUR 979
Description: Assay Kit for detection of JNK in the research laboratory

Akt Assay Kit

55R-1409 40 assays
EUR 979
Description: Assay Kit for detection of Akt in the research laboratory

Ammonia Assay Kit

55R-1410 100 assays
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Description: Assay Kit for detection of Ammonia in the research laboratory

Cobalt Assay Kit

55R-1435 100 assays
EUR 621
Description: Assay Kit for detection of Cobalt in the research laboratory

Nickel Assay Kit

55R-1436 100 assays
EUR 621
Description: Assay Kit for detection of Nickel in the research laboratory

Chloride Assay Kit

55R-1437 100 assays
EUR 484
Description: Assay Kit for detection of Chloride in the research laboratory

Aspartate Assay Kit

55R-1438 100 assays
EUR 673
Description: Assay Kit for detection of Aspartate in the research laboratory

Hydroxyproline Assay Kit

55R-1439 100 assays
EUR 844
Description: Assay Kit for detection of Hydroxyproline in the research laboratory

Phenylalanine Assay Kit

55R-1442 100 assays
EUR 654
Description: Assay Kit for detection of Phenylalanine in the research laboratory

Phosphatidylcholine Assay Kit

55R-1443 100 assays
EUR 673
Description: Assay Kit for detection of Phosphatidylcholine in the research laboratory

Glucose Assay Kit

55R-1449 100 assays
EUR 706
Description: Assay Kit for detection of Glucose in the research laboratory

Lactate Assay Kit

55R-1450 100 assays
EUR 844
Description: Assay Kit for detection of Lactate in the research laboratory

Pyruvate Assay Kit

55R-1452 100 assays
EUR 844
Description: Assay Kit for detection of Pyruvate in the research laboratory

Adipogenesis Assay Kit

55R-1454 100 assays
EUR 586
Description: Assay Kit for detection of Adipogenesis in the research laboratory

Glucose Assay Kit

55R-1458 100 assays
EUR 740
Description: Assay Kit for detection of Glucose in the research laboratory

Galactose Assay Kit

55R-1459 100 assays
EUR 740
Description: Assay Kit for detection of Galactose in the research laboratory

Maltose Assay Kit

55R-1460 100 assays
EUR 723
Description: Assay Kit for detection of Maltose in the research laboratory

Fructose Assay Kit

55R-1461 100 assays
EUR 689
Description: Assay Kit for detection of Fructose in the research laboratory

Ethanol Assay Kit

55R-1462 100 assays
EUR 774
Description: Assay Kit for detection of Ethanol in the research laboratory

Galactose Assay Kit

55R-1463 100 assays
EUR 706
Description: Assay Kit for detection of Galactose in the research laboratory

Lactose Assay Kit

55R-1466 100 assays
EUR 706
Description: Assay Kit for detection of Lactose in the research laboratory

Creatinine Assay Kit

55R-1467 100 assays
EUR 638
Description: Assay Kit for detection of Creatinine in the research laboratory

Sucrose Assay Kit

55R-1468 100 assays
EUR 689
Description: Assay Kit for detection of Sucrose in the research laboratory

Lactate Assay Kit

55R-1469 100 assays
EUR 844
Description: Assay Kit for detection of Lactate in the research laboratory

Maltose Assay Kit

55R-1470 100 assays
EUR 706
Description: Assay Kit for detection of Maltose in the research laboratory

Glutamate Assay Kit

55R-1471 100 assays
EUR 740
Description: Assay Kit for detection of Glutamate in the research laboratory

Fumarate Assay Kit

55R-1475 100 assays
EUR 706
Description: Assay Kit for detection of Fumarate in the research laboratory

Creatine Assay Kit

55R-1476 100 assays
EUR 654
Description: Assay Kit for detection of Creatine in the research laboratory

Sarcosine Assay Kit

55R-1477 100 assays
EUR 654
Description: Assay Kit for detection of Sarcosine in the research laboratory

Malate Assay Kit

55R-1478 100 assays
EUR 673
Description: Assay Kit for detection of Malate in the research laboratory

Glycogen Assay Kit

55R-1481 100 assays
EUR 844
Description: Assay Kit for detection of Glycogen in the research laboratory

Starch Assay Kit

55R-1482 100 assays
EUR 673
Description: Assay Kit for detection of Starch in the research laboratory

Alanine Assay Kit

55R-1483 100 assays
EUR 654
Description: Assay Kit for detection of Alanine in the research laboratory
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