Enhanced HIV-1 Replication in CD4+ T Cells Derived from Individuals with Latent Mycobacterium tuberculosis Infection.

Mycobacterium tuberculosis (Mtb) and HIV co-infection increases mortality, accelerating progression to AIDS and worsen the disease tuberculosis. However, the impact of existing Mtb infection in subsequent HIV infection has not been fully explored.

We hypothesize that Mtb infection immunology create an environment that affect course of HIV infection and to investigate whether there was an impact Mtb infection of CD4 + T cell susceptibility to HIV-1 infection.Plasma and CD4 + T cells isolated from the blood of HIV-negative spectrum Mtb infection and individual control of non-Mtb-infected analyzed for markers of inflammation and cell phenotype T cell CD4 + T-cells infected with HIV-1 in vitro and monitored for viral replication.

We observable differences in pro-inflammatory cytokines and the relative proportion of a memory T cell subsets depending on the status of Mtb infection. Cells CD4 + T-cells derived from individuals with latent Mtb infection is supported by more efficient HIV-1 transcription, release, and replication. Enhanced HIV-1 replication correlated with a higher percentage of CD4 + TEM and TTD-existing cells.Pre Mtb infection immunology create an environment that reflects the status of Mtb infection and the effect of CD4 + T cell susceptibility to HIV-1 replication. These findings provide insight into the cellular and molecular how there Mtb infection with HIV-1 pathogenesis influence.

NanoGram DNA Assay Reagent

NDA500 500 assays
EUR 187.8
Description: This product includes 5 ml of 10 x Reagent D. It is for 2000 assays using 384-well plates or 500 assays using 96-well plates. Cuvettes may also be used for the assay.

QuantiFluo™ DNA Assay Kit

QFDN-250 250
EUR 359
Description: For quantitative determination of DNA. Key Features: Sensitive and accurate. Linear detection range 2 ng to 40 ng (100 - 2,000 ng/mL) calf thymus DNA in 96-well plate assay. Simple and high-throughput. The "mix-and-read" procedure involves addition of a single working reagent and reading the fluorescence intensity. Can be readily automated as a high-throughput assay for thousands of samples per day. Low interference. RNA, salt (up to 3M NaCl), detergent (< 0.01% SDS) and common DNA extraction buffer do not interfere in the assay. Method: FL350/450nm. Samples: Plasmid DNA, genomic DNA, cDNA, DNA following polymerase chain reaction, and DNA extracted from gel and other matrices. Species: All. Procedure: Assay takes 5 min. Kit size: 250 tests. Detection limit: 100 ng/mL.

ApoBrdU DNA Fragmentation Assay Kit

55R-1396 60 assays
EUR 1299.6
Description: DNA Fragmentation Assay Kit for use in the research laboratory

ApoBrdU DNA Fragmentation Assay Kit

K2070-60 60 assays
EUR 919.2

ApoBrdU DNA Fragmentation Assay Kit

K401-60 each
EUR 927.6

ApoDIRECT DNA Fragmentation Assay Kit

55R-1397 50 assays
EUR 1303.2
Description: DNA Fragmentation Assay Kit for use in the research laboratory

ApoDIRECT DNA Fragmentation Assay Kit

K2071-50 50 assays
EUR 919.2

ApoDIRECT DNA Fragmentation Assay Kit

K402-50 each
EUR 952.8

DNA Quantification Assay Kit (Fluorometric)

K539-200 each
EUR 314.4

DNA Quantification Assay Kit (Fluorometric)

K539-2000 each
EUR 470.4

Human DNA Polymerase Gamma Assay Kit

DPG100K 100 assays
EUR 372.78
Description: This product includes all the assay kit components except the enzyme for 100 assays in a 384-well plate assay format: 400 ul of 10 x Buffer, 33 ul of 100 x DNA template, 33 ul of 100 x dNTP mix, 1550 ul of 2 x Dye, 1550 ul of 50 mM EDTA.

Human DNA Polymerase Alpha Assay Kit

HDPA100K 100 assays
EUR 278.4
Description: This product includes all the assay kit components except the enzyme for 100 assays in a 384-well plate assay format: 400 ul of 10 x Buffer, 33 ul of 100 x DNA template, 33 ul of 100 x dNTP mix, 1550 ul of 2 x Dye, 1550 ul of 50 mM EDTA. The kit does not include the enzyme.

ApoBrdU-IHC DNA Fragmentation Assay Kit

55R-1398 50 assays
EUR 1303.2
Description: DNA Fragmentation Assay Kit for use in the research laboratory

ApoBrdU-IHC DNA Fragmentation Assay Kit

K2072-50 50 assays
EUR 1002

ApoBrdU-IHC DNA Fragmentation Assay Kit

K403-50 each
EUR 952.8

DNA Topoisomerase DNA decatenation Assay Kit (enzyme not included)

DDC020K 20 assays
EUR 184.03
Description: This product includes 150 ul of 10 x assay buffer (Buffer T4), 105 ul of 10 x concatenated DNA, 30 ul of 50 x ATP (10 mM),120 ul of 0.4 M EDTA, 160 ul of 20 x fluorescence dye and 20 spin columns for 20 DNA decatenation assays. The assay buffer is optimized for bacterial topoisomerase IV. Bacterial topoisomerase IV enzymes are provided separately.

EpiQuik In Situ DNA Damage Assay Kit 

P-6001
  • EUR 1241.46
  • EUR 552.20
  • 2x96 assays
  • 96 Assays

Human TDP1 Assay Kit (DNA/Top1 Complex)

TG1004-1A 100 assays
EUR 672

Human TDP1 Assay Kit (DNA/Top1 Complex)

TG1004-2A 250 assays
EUR 792

Topoisomerase I Assay Kit (62.5ug SC DNA)

TG1015-2 250 assays
EUR 496.8

Topoisomerase I Assay Kit (25ug SC DNA)

TG1015-1 100 assays
EUR 362.4

Human DNA Polymerase Beta Assay Kit Plus

DPB100KE 100 assays
EUR 448.28
Description: This product includes 0.800 ml of 10 x Buffer BP, 0.055 ml of 100x DNA template, 0.055 ml of 100 x dNTP mix, 0.055 ml of 100 x human DNA polymerase beta, 22 ml of Reagent U and 0.420 ml of 10 x fluorescence dye for 100 assays of human DNA polymerase reactions in a 96-well plate format.

Human DNA Polymerase Gamma Assay Kit Plus

DPG100KE 100 assays
EUR 467.15
Description: This product includes all the assay kit components for 100 assays in 384-well plate assay format: 400 ul of 10 x Buffer, 33 ul of 100 x DNA template, 33 ul of 100 x dNTP mix, 33 ul of 100 x human DNA polymerase gamma, 1550 ul of 2 x Dye, 1550 ul of 50 mM EDTA.

Human DNA Polymerase Alpha Assay Kit Plus

HDPA100KE1 100 assays
EUR 624.67
Description: This product includes all the assay kit components for 100 assays in 384-well plate assay format: 400 µl of 10 x Buffer, 33 µl of 100 x DNA template, 33 µl of 100 x dNTP mix, 30 µl of 100 x human DNA polymerase alpha (4 µM), 1550 µl of 2 x Dye, 1550 µl of 50 mM EDTA.

DNA polymerase Assay Kit (enzyme not included)

DPA100K 100 assays
EUR 278.4
Description: This product includes 500 ul of 10 x Buffer DP, 35 ul of 100 x DNA template, 35 ul of 100x dNTP mix and 320 ul of 10x fluorescence dye for 100 assays of DNA polymerase reactions in a 384-well assay format. The assay conditions are optimized for bacterial DNA polymerase III alpha subunit. Enzyme is not included in the kit.

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase)

TG2000G-7KIT 2000 assays
EUR 3412.8

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase)

TG2000G-5KIT 1000 assays
EUR 1934.4

EvaEZ Flurometric DNA Polymerase Activity Assay (200 rxn)

29051 2mL
EUR 550.8
Description: Minimum order quantity: 1 unit of 2mL

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase)

TG2000G-1KIT 100 assays
EUR 456

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase)

TG2000G-3KIT 500 assays
EUR 1182

Human Cytomegalovirus (HCMV) DNA Polymerase Assay Kit

HCMV100K 100 assays
EUR 278.4
Description: This product includes all the assay kit components for 100 assays in 384-well plate assay format: 400 ul of 10 x Buffer, 33 ul of 100 x DNA template, 33 ul of 100 x dNTP, 1550 ul of 2 x Dye and 1550 ul of 50 mM EDTA.

HIF-1 Alpha DNA Binding Activity Assay Kit

CBA-282 96 assays
EUR 762
Description: Cell Biolabs? HIF-1 Alpha DNA Binding Activity Assay Kit is an immunoassay developed for rapid detection of activated HIF-1 in any protein sample. Active HIF-1 complex is captured on a double stranded oligonucleotide containing an HRE that is attached to the well. HIF-1 Alpha is then detected with an anti-HIF-1 Alpha antibody followed by an HRP conjugated secondary antibody. Each kit provides sufficient reagents to perform up to a total of 96 assays, and can detect HIF-1 Alpha from human, mouse, or rat. The HIF-1 DNA Binding Activity Assay takes only 4.5 hours to complete compared to a standard 3 day electromobility shift (EMSA) method.

EpiQuik DNA Demethylase Activity/Inhibition Assay Kit 

P-3019
  • EUR 1067.46
  • EUR 477.40
  • EUR 710.60
  • 96 Assays
  • 48 Assays
  • 96 Assays

Gel Shift Single-strand DNA Binding Assay Kit

GSSB100K 100 assays
EUR 112.31
Description: This product includes 150 µl of 10 x Buffer, 150 µl of 10 x ssDNA (a 45-mer single-strand DNA) and 100 µl of 4 x gel loading buffer.

DNA Topoisomerase I Assay Kit (enzyme not included)

DRA020K 20 assays
EUR 184.03
Description: This product includes the reaction buffer (T1 Buffer), supercoiled plasmid DNA and fluorescence dye H19 for assaying 20 DNA relaxation reactions in a 96-well plate assay format or 40 assays in a 384-well assay format. The reaction buffer is optimized for bacterial topoisomerase I.

S. aureus Gyrase DNA Supercoiling Assay Plus-100

DSA100KSE 100 assays
EUR 681.29
Description: This product includes 500 ul of 10 x Buffer T2, 410 ul of 10 x relaxed DNA, 22 ul of 1500 x H19 dye, 450 ul of 10 x ATP, 43 ul 7.5 uM S. aureus gyrase, 820 ul of 2 M potassium glutamate and 3000 ul of 10 x H19 dilution buffer. It is for 100 assays in a 96-well plate format.

Human Topoisomerase I DNA Relaxation Assay Kit -100

HRA100K 100 assays
EUR 460.55
Description: This product includes 480 ul of 10 x Buffer HT1, 405 ul of 10 x supercoiled plasmid DNA, 20 ul of 1500 x Dye H19 and 3000 ul of 10 x H19 dilution buffer. It is for 100 DNA relaxation assays in a 96-well plate format or 200 assays in a 384-well assay format. Human topo I enzyme in not included and can be purchased separately.

E. coli DNA Helicase ATPase assay Kit Plus-100

DNAB100KE 100 assays
EUR 444.91
Description: This product includes 0.500 ml of 10 x assay buffer, 0.035 ml of 100 x DNA, 0.030 ml of 100 x E. coli DNA helicase, 0.035 ml of 100 x ATP and 5 ml of dye for 100 assays in a 384-well assay format.

E. coli DNA Helicase ATPase assay Kit Plus-500

DNAB500KE 500 assays
EUR 1396.74
Description: This product includes 2 ml of 10 x assay buffer, 0.170 ml of 100 x DNA, 0.150 ml of 100 x E. coli DNA helicase, 0.170 ml of 100 x ATP and 25 ml of dye for 500 assays in a 384-well assay format.

E. coli DNA Primase Assay Kit (enzyme not included)

EGA100K 100 assays
EUR 278.4
Description: This product includes 600 ul of 10 x assay buffer, 45 ul of 100 x DNA template, 45 ul of 100 x NTP mix and 850 ul of 10 x fluorescence dye for 100 assays of E. coli DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format. The kit does not include the enzyme.

S. aureus DNA Helicase ATPase assay Kit Plus-100

DNAB100KS 100 assays
EUR 444.91
Description: This product includes 0.500 ml of 10 x assay buffer, 0.035 ml of 100 x DNA, 0.030 ml of 100 x S. aureus DNA helicase, 0.035 ml of 100 x ATP and 5 ml of dye for 100 assays in a 384-well assay format.

S. aureus DNA Helicase ATPase assay Kit Plus-500

DNAB500KS 500 assays
EUR 1491.11
Description: This product includes 2 ml of 10 x assay buffer, 0.170 ml of 100 x DNA, 0.150 ml of 100 x S. aureus DNA helicase, 0.170 ml of 100 x ATP and 25 ml of dye for 500 assays in a 384-well assay format.

S. aureus DNA Primase Assay Kit (enzyme not included)

AGA100K 100 assays
EUR 278.4
Description: This product includes 600 ul of 10 x assay buffer, 45 ul of 100 x DNA template, 45 ul of 100 x NTP mix and 850 ul of 10 x fluorescence dye for 100 assays of S. aureus DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format. The kit does not include the enzyme.

EpiQuik DNA Demethylase Activity/Inhibition Assay Ultra Kit 

P-3008
  • EUR 1032.66
  • EUR 454.30
  • EUR 686.40
  • 96 Assays
  • 48 Assays
  • 96 Assays

S. aureus DNA Primase Assay Kit Plus (enzyme included)

AGA100KE 100 assays
EUR 444.91
Description: This product includes all the kit components in S. aureus DNA Primase Assay Kit (Catalog No. AGA100K ) plus 45 ul of 100 x S. aureus primase. It is for 100 assays of S. aureus DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format.

Gel Shift Single-strand DNA Binding Assay Kit Plus

GSSB100KE 100 assays
EUR 332.56
Description: This product includes 150 µl of 10 x Buffer, 150 µl of 10 x ssDNA, 150 µl of 2 mg/ml E. coli single-strand DNA binding protein SSB and 100 µl of 4 x gel loading buffer.

H. influenzae DNA Helicase ATPase assay Kit Plus-100

DNAB100KH 100 assays
EUR 444.91
Description: This product includes 0.500 ml of 10 x assay buffer, 0.035 ml of 100 x DNA, 0.030 ml of 100 x H. influenzae DNA helicase, 0.035 ml of 100 x ATP and 5 ml of dye for 100 assays in a 384-well assay format.

S. pneumoniae DNA Helicase ATPase assay Kit Plus-100

DNAB100KN 100 assays
EUR 444.91
Description: This product includes 0.500 ml of 10 x assay buffer, 0.035 ml of 100 x DNA, 0.030 ml of 100 x S. pneumoniae DNA helicase, 0.035 ml of 100 x ATP and 5 ml of dye for 100 assays in a 384-well assay format.

P. aeruginosa DNA Helicase ATPase assay Kit Plus-100

DNAB100KP 100 assays
EUR 444.91
Description: This product includes 0.500 ml of 10 x assay buffer, 0.035 ml of 100 x DNA, 0.030 ml of 100 x P. aeruginosa DNA helicase, 0.035 ml of 100 x ATP and 5 ml of dye for 100 assays in a 384-well assay format.

H. influenzae DNA Helicase ATPase assay Kit Plus-500

DNAB500KH 500 assays
EUR 1491.11
Description: This product includes 2 ml of 10 x assay buffer, 0.170 ml of 100 x DNA, 0.150 ml of 100 x H. influenzae DNA helicase, 0.170 ml of 100 x ATP and 25 ml of dye for 500 assays in a 384-well assay format.

S. pneumoniae DNA Helicase ATPase assay Kit Plus-500

DNAB500KN 500 assays
EUR 1491.11
Description: This product includes 2 ml of 10 x assay buffer, 0.170 ml of 100 x DNA, 0.150 ml of 100 x S. pneumoniae DNA helicase, 0.170 ml of 100 x ATP and 25 ml of dye for 500 assays in a 384-well assay format.

P. aeruginosa DNA Helicase ATPase assay Kit Plus-500

DNAB500KP 500 assays
EUR 1491.11
Description: This product includes 2 ml of 10 x assay buffer, 0.170 ml of 100 x DNA, 0.150 ml of 100 x P. aeruginosa DNA helicase, 0.170 ml of 100 x ATP and 25 ml of dye for 500 assays in a 384-well assay format.

S. pneumonia DNA Primase Assay Kit (enzyme not included)

PGA100K 100 assays
EUR 278.4
Description: This product includes 600 ul of 10 x assay buffer, 45 ul of 100 x DNA template, 45 ul of 100 x NTP mix and 850 ul of 10 x fluorescence dye for 100 assays of S. pneumoniae DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format. The kit does not include the enzyme.

Human DNA polymerase beta assay kit (enzyme not included)

DPB100K 100 assays
EUR 278.4
Description: This product includes all the assay reagents except the enzyme for 100 assays of human DNA polymerase beta reactions in a 96-well plate format.

S. pneumonia DNA Primase Assay Kit Plus (enzyme included)

PGA100KE 100 assays
EUR 444.91
Description: This product includes all the kit components in S. pneumoniae DNA Primase Assay Kit (Catalog No. PGA100K ) plus 45 ul of 100 x S. pneumoniae primase. It is for 100 assays of S. pneumoniae DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format.

H. influenzae DNA Primase Assay Kit (enzyme not included)

HGA100K 100 assays
EUR 278.4
Description: This product includes 600 ul of 10 x assay buffer, 45 ul of 100 x DNA template, 45 ul of 100 x NTP mix and 850 ul of 10 x fluorescence dye for 100 assays of H. influenzae DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format. The kit does not include the enzyme.

Human Topoisomerase I DNA Relaxation Assay Kit Plus -1000

HRA1000KE 100 assays
EUR 3100.19
Description: This product includes 4800 ul of 10 x Buffer HT1, 4050 ul of 10 x supercoiled plasmid DNA, 40 ul of 1000 x human topoisomerase I enzyme (500U/ul), 170 ul of 1500 x Dye H19 and 30 ml of 10 x H19 dilution buffer. This product includes all the reagents for 1000 DNA relaxation assays in a 96-well plate format or 2000 assays in a 384-well assay format.

Human Topoisomerase I DNA Relaxation Assay Kit Plus -100

HRA100KE 100 assays
EUR 590.51
Description: This product includes 480 ul of 10 x Buffer HT1, 405 ul of 10 x supercoiled plasmid DNA, 10 ul of 1000 x human topoisomerase I enzyme (500U/ul), 20 ul of 1500 x Dye H19 and 3000 ul of 10 x H19 dilution buffer. This product includes all the reagents for 100 DNA relaxation assays in a 96-well plate format or 200 assays in a 384-well assay format.

EpiQuik DNA Methyltransferase (DNMT) Activity/Inhibition Assay Kit 

P-3001
  • EUR 1050.06
  • EUR 424.60
  • EUR 712.80
  • 96 Assays
  • 48 Assays
  • 96 Assays

NAD-dependent DNA Ligase Assay Kit (enzyme not included)

NLA100K 100 assays
EUR 350.75
Description: This product includes 800 ul of 10 x buffer, 44 ul of 100x DNA substrate, 44 ul of 100 x NAD+, 21 ml of Reagent T and 220 ul of 10 x fluorescence dye for 100 assays. The kit does not include ligase that can be purchased separately (please see the information of related products).

H. influenzae DNA Primase Assay Kit Plus (enzyme included)

HGA100KE 100 assays
EUR 444.91
Description: This product includes all the kit components in H. influenzae DNA Primase Assay Kit (Catalog No. HGA100K ) plus 45 ul of 100 x H. influenzae primase-helicase complex. It is for 100 assays of H. influenzae DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format.

Topoisomerase I Assay Kit (62.5ug SC DNA + 250u Human Topo I)

TG1015-2A 250 assays
EUR 792

DNA Topoisomerase II (Gyrase) Assay Kit (enzyme not included)

DSA020K 20 assays
EUR 184.03
Description: This product includes the reaction buffer (T2 Buffer), relaxed plasmid DNA and fluorescence dye H19 for 20 assays of DNA supercoiling reactions a 96-well plate assay format or 40 assays in a 384-well assay format.

Topoisomerase I Assay Kit (25ug SC DNA +100u Human Topo I)

TG1015-1A 100 assays
EUR 483.6

Topoisomerase I Assay Kit (125ug SC DNA + 500u Human Topo I)

TG1015-3A 500 assays
EUR 926.4

H influenzae DNA Polymerase Assay Kit Plus (enzyme included)

DPA100KH 100 assays
EUR 444.91
Description: This product includes all the reagents in the DNA Polymerase III Alpha Assay Kit (Catalog No. DPA100K) plus 35 ul of 100 x H. influenzae DNA polymerase III alpha subunit.

S. pneumoniae DNA Polymerase Assay Kit Plus (enzyme included)

DPA100KN 100 assays
EUR 444.91
Description: This product includes all the reagents in the DNA Polymerase III Alpha Assay Kit (Catalog No. DPA100K) plus 35 ul of 100 x S. pneumoniae DNA polymerase III alpha subunit.

Gel-Based Human Topoisomerase I DNA relaxation Assay Kit

GHRA100KE 100 assays
EUR 414.97
Description: This product includes 400 ul of 10 x Buffer HT1, 100 ul of 0.25 mg/ml supercoiled DNA, 550 ul of 5 x Gel loading buffer and 10 ul of 500 U/ul human topoisomerase I enzyme.

EZClick? TUNEL ? in situ DNA Fragmentation/Apoptosis Assay Kit

K191-100 each
EUR 639.6

E. coli DNA polymerase Assay Kit Plus (E. coli DNA pol III alpha subunit included)

DPA100KE 100 assays
EUR 444.91
Description: This product includes all the reagents in the DNA Polymerase III Alpha Assay Kit (Catalog No. DPA100K) plus 35 ul of 100 x E. coli DNA polymerase III alpha subunit.

Human Cytomegalovirus (HCMV) DNA Polymerase Assay Kit Plus-100

HCMV100KE 100 assays
EUR 444.91
Description: This product includes all the assay kit components for 100 assays in 384-well plate assay format: 400 ul of 10 x Buffer, 33 ul of 100 x DNA template, 33 ul of 100 x dNTP mix, 33 ul of 100 x HCMV DNA polymerase, 1550 ul of 2 x Dye, 1550 ul of 50 mM EDTA.

96-well E. coli Topo IV DNA Cleavage Assay Kit Plus

T4C96KE 96 assays
EUR 597.7
Description: This product includes all the components in TDC96K plus 26 ul of 100 x E. coli Topo IV.

Gel-Based E. coli Topoisomerase I DNA relaxation Assay Kit

GDRA100KE 100 assays
EUR 399.28
Description: This product includes all the reagents for 100 samples in gel-based assays of E. coli topo I DNA relaxation activity. It This product includes 300 µl of 10 x Buffer T1, 100 µl of 250 mg/ml supercoiled DNA, 550 µl of 5 x Gel loading buffer and 10 µl of 4 µM E. coli topoisomerase I enzyme.

S. aureus Gyrase DNA Supercoiling Assay Kit Plus (enzyme included)

DSA020KSE 20 assays
EUR 240.65
Description: This product includes160 ul of 10 x Buffer T2, 84 ul of 10 x relaxed DNA, 6 ul of 1500 x H19 dye, 90 ul of 10 x ATP, 10 ul 7.5 uM S. aureus gyrase, 180 ul of 2 M potassium glutamate and 550 ul of 10 x H19 dilution buffer. It is for 20 assays in a 96-well plate format.

Gel-based Human Topoisomerase II DNA Decatenation Assay Kit Plus

HDD100KEG 100 assays
EUR 357.68
Description: This product includes 300 ul of 10 x assay buffer, 200 ul of 10 x concatenated DNA (30 ug/ml), 200 ul of 10 x ATP, 200 ul of 0.5 M EDTA, 15 ul of 200 x human topoisomerase II alpha (10 U/µl), 1 ml of enzyme dilution buffer and 500 ul of 5 x gel-loading buffer for 100 assays of human DNA decatenation reactions.

96-well Topoisomerase DNA Cleavage Assay Kit (enzyme not included)

TDC96K 96 assays
EUR 510.52
Description: This product includes 300 ul of 10 x reaction buffer, 30 ul of 10 x DNA, 260 ul of SDS solution, 30 ul of 100 mM ATP, 260 ul of proteinase K solutions, 10 ml of TDC matrix, 6 ml of rinse buffer, 500 ul of 10 x dye, a black receiver plate, a V-bottom reaction plate and a TDC filter plate. Topoisomerase is not included in the kit. A plate filtration device (see Note below) and a vacuum line are needed for the plate filtration process.

E. coli Topo IV DNA Relaxation Assay Kit Plus (enzyme included)

T4RA-100KE 100 assays
EUR 561.75
Description: This product includes 480 ul of 10 x Buffer, 405 ul of 10 x supercoiled plasmid DNA, 45 ul of 100 x E. coli topoisomerase IV, 420 ul of 10 mM ATP and 20 ul of 1500 x fluorescence dye H19 for 100 assays of DNA relaxation reactions in a 96-well assay format.

Human topoisomerase I DNA relaxation assay kit (enzyme not included)

HRA020K 20 assays
EUR 184.03
Description: This product includes 160 ul of 10 x Buffer HT1, 84 ul of 10 x supercoiled plasmid DNA, 8 ul of 1500 x Dye H19 and 500 ul of 10 x H19 dilution buffer. It is for 20 DNA relaxation assays in a 96-well plate format or 40 assays in a 384-well assay format. Human topo I enzyme in not included and can be purchased separately.

P. aeruginosa Gyrase DNA Supercoiling Assay Kit Plus (enzyme included)

DSA100KP 100 assays
EUR 590.51
Description: This product includes all the reagents for 100 assays of P. aeruginosa gyrase DNA supercoiling activity. This product includes 600 ul of 10 x Buffer T2, 405 ul of 10 x relaxed DNA, 20 ul of 1500 x H19 dye, 450 ul of 10 x ATP, 3000 ul of 10 x H19 dilution buffer and 50 ul 100 x P. aeruginosa gyrase.

EpiQuik DNA Methyltransferase (DNMT) Activity/Inhibition Assay Kit (Fluorometric) 

P-3004
  • EUR 1067.46
  • EUR 429.00
  • EUR 710.60
  • 96 Assays
  • 48 Assays
  • 96 Assays

S. aureus Topo IV DNA Relaxation Assay Kit Plus (enzyme included)

T4RA-100KS 100 assays
EUR 561.75
Description: This product includes 480 ul of 10 x Buffer, 405 ul of 10 x supercoiled plasmid DNA, 45 ul of 100 x S. aureus topoisomerase IV, 420 ul of 10 mM ATP and 20 ul of 1500 x fluorescence dye H19 for 100 assays of DNA relaxation reactions in a 96-well assay format.

Human Topoisomerase II DNA Decatenation Assay Kit (enzyme not included)

HDC020K 20 assays
EUR 184.03
Description: This product includes the assay buffer, concatenated DNA, spin columns and loading solution for 20 assays of DNA decatenation reactions. The assay buffer is optimized for human topoisomerase II alpha.

Human Topoisomerase II DNA Decatenation Assay Kit Plus (enzyme included)

HDC020KE 20 assays
EUR 240.65
Description: This product includes the assay buffer, concatenated DNA, human topoisomerase II alpha, spin columns and loading solution for 20 assays of DNA decatenation reactions. The assay buffer is optimized for human topoisomerase II alpha.

96-Well Topoisomerase DNA Decatenation Assay Kit (enzyme not included)

TDD96K 96 assays
EUR 526.61
Description: This product includes 600 ul of 10 x assay buffer, 500 ul of 10 x concatenated DNA, 110 ul of 10 mM ATP, 600 ul of 0.4 M EDTA, 260 ul of 20 x fluorescence dye, 2 ml of 10 x rinse buffer, one V-bottom plate, a TDD filter plate and one black 96-well plates for 96 assays of DNA decatenation reactions. The assay buffer is optimized for bacterial topoisomerase IV. DNA decatenation enzyme is not included. This kit can be used for DNA decatenation assays of any bacterial topoisomerase IV (the parC-parE complex) enzymes or gyrases.

E. coli DNA Topoisomerase IV Assay Kit Plus-100 (enzyme included)

DDC100KE 100 assays
EUR 681.29
Description: This product includes the 600 ul of assay buffer (Buffer T4), 520 ul of 10 x concatenated DNA, 120 ul of 50 x ATP (10 mM), 550 ul of 0.4 M EDTA, 780 ul of 20 x fluorescence dye, 100 spin columns and 55ul of 100 x E.coli topoisomerase IV (500 nM) for 100 E. coli topoisomerase IV DNA decatenation assays.

E. coli DNA Topoisomerase I Assay Kit Plus-100 (enzyme included)

DRA100KE 100 assays
EUR 590.51
Description: This product includes 480 ul of 10 x Buffer T1, 405 ul of 10 x supercoiled plasmid DNA, 20 ul of 1500 x Dye H19, 3000 ul of 10 x H19 dilution buffer and 42 ul of 100 x E. coli topoisomerase I. It is for 100 DNA relaxation assays in a 96-well plate format or 200 assays in a 384-well assay format

DNA Topoisomerase I assay reagent Set for HTS (enzyme not included)

DRA1000 1000 assays
EUR 452.05
Description: This product includes the reaction buffer and fluorescence dye H19 for 1000 assays of DNA relaxation reactions in a 96-well plate assay format or 2000 assays in a 384-well assay format.

S. pneumoniae Topo IV DNA Relaxation Assay Kit Plus (enzyme included)

T4RA-100KN 100 assays
EUR 561.75
Description: This product includes 480 ul of 10 x Buffer, 405 ul of 10 x supercoiled plasmid DNA, 45 ul of 100 x S. pneumoniae topoisomerase IV, 420 ul of 10 mM ATP and 20 ul of 1500 x fluorescence dye H19 for 100 assays of DNA relaxation reactions in a 96-well assay format.

P. aeruginosa Topo IV DNA Relaxation Assay Kit Plus (enzyme included)

T4RA-100KP 100 assays
EUR 561.75
Description: This product includes 480 ul of 10 x Buffer, 405 ul of 10 x supercoiled plasmid DNA, 45 ul of 100 x P. aeruginosa topoisomerase IV, 420 ul of 10 mM ATP and 20 ul of 1500 x fluorescence dye H19 for 100 assays of DNA relaxation reactions in a 96-well assay format.

Gel-Based E. coli Topoisomerase IV DNA Decatenation Assay Kit Plus

GDDA100KE 100 assays
EUR 399.28
Description: This product includes all the reagents for 100 samples in gel-based assays of E. coli topoisomerase IV DNA decatenation activity. It includes 300 µl of 10 x Buffer, 205 µl of 60 mg/ml concatenated DNA (kDNA), 205 µl of 10 mM ATP, 550 µl of 5 x Gel loading buffer and 22 µl of 10 µM E.coli topoisomerase IV (the parC-parE complex).

Gel-based E. coli DNA Topoisomerase II (Gyrase) Assay Kit Plus-100 (for 100 assays)

GDSA100KE 100 assays
EUR 399.28
Description: This product includes 400 ul of 10 x Buffer, 105 ul of 250 ug/ml relaxed DNA, 220 ul of 10 mM ATP, 550 ul of 5 x Gel loading buffer and 25 ul of 2000 nM E.coli gyrase.

Human topoisomerase I DNA relaxation assay HTS kit (enzyme not included)

HRA1000 100 assays
EUR 452.05
Description: This product includes 4800 ul of 10 x Buffer HT1, 170 ul of 1500 x Dye H19 and 30 ml of 10 x H19 dilution buffer. It is for 1000 DNA relaxation assays in a 96-well plate format or 2000 assays in a 384-well assay format. Supercoiled DNA and human topo I enzyme can be purchased separately.

Epigenase Thymine DNA Glycosylase (TDG) Activity/Inhibition Assay Kit (Colorimetric) 

P-3094
  • EUR 1084.86
  • EUR 429.00
  • EUR 723.80
  • 96 Assays
  • 48 Assays
  • 96 Assays

AccuClear Ultra High Sensitivity dsDNA Quantitation Assay kit with 1 DNA Standard (2000 assays)

31029 1kit
EUR 616.8
Description: Minimum order quantity: 1 unit of 1kit

96-well E. coli Gyrase DNA Cleavage Assay Kit Plus (enzyme included)

T2C96KE 96 assays
EUR 597.7
Description: This product includes 300 ul of 10 x reaction buffer, 30 ul of 10 x DNA, 260 ul of SDS solution, 30 ul of 100 mM ATP, 260 ul of proteinase K solutions, 10 ml of TDC matrix, 6 ml of rinse buffer, 500 ul of 10 x dye, a black receiver plate, a V-bottom reaction plate, 26 ul of 100 x E. coli Gyrase and a TDC filter plate. A plate filtration device and a vacuum line are needed for the plate filtration process.

E. coli DNA Primase Assay Kit Plus (E. coli primase-helicase included)

EGA100KE 100 assays
EUR 444.91
Description: This product includes all the kit components in E. coli DNA Primase Assay Kit (Catalog No. EGA100K ) plus 45 ul of 100 x E. coli primase-helicase complex. It is for 100 assays of E.coli DNA primase reactions in a 96-well plate format or 200 assays in 384-well assay format.

Human Topoisomerase II DNA Decatenation Assay Kit Plus-100 (enzyme included)

HDC100KE 100 assays
EUR 861.05
Description: This product includes the reaction buffer, concatenated DNA, human topoisomerase II alpha, spin columns and loading solution for 100 assays of DNA decatenation reactions.

Human Topoisomerase II DNA Decatenation Assay Reagent Set (enzyme not included)

HDC100 100 assays
EUR 423.74
Description: This product includes the reaction buffer, spin columns and loading solution for 100 assays of DNA decatenation reactions. Enzyme and concatenated DNA are not included in the set.

96-Well Human Topo II DNA Decatenation Assay Kit Plus (enzyme included)

HDD96KE 96 assays
EUR 690.28
Description: This product includes the assay buffer, concatenated DNA, human topo II alpha, ATP, fluorescence dye, rinse buffer and a TDD filter plate for 96 assays of human topo II DNA decatenation reactions.

E. coli DNA Topoisomerase IV Assay Kit Plus (E. coli Topo IV included)

DDC020KE 20 assays
EUR 221.78
Description: This product includes all the components in DNA Topoisomerase IV Assay Kit (Catalog No. DDC020K)plus 12ul of 100 x E.coli topoisomerase IV (500 nM) for 20 E. coli topoisomerase IV DNA decatenation assays.

E. coli DNA Topoisomerase I Assay Kit Plus (E. coli Topo I included)

DRA020KE 20 assays
EUR 221.78
Description: This product includes 160 ul of 10 x Buffer T1, 84 ul of 10 x supercoiled plasmid DNA, 10 ul of 100 x E. coli topoisomerase I, 8 ul of 1500 x Dye H19 and 500 ul of 10 x H19 dilution buffer. It is for 20 DNA relaxation assays in a 96-well plate format or 40 assays in a 384-well assay format.

E. coli DNA Topoisomerase II (Gyrase) Assay Kit Plus-100 (enzyme included)

DSA100KE 100 assays
EUR 590.51
Description: This product includes all the reagents for 100 assays of E. coli gyrase DNA supercoiling activity. This product includes 600 ul of 10 x Buffer T2, 405 ul of 10 x relaxed DNA, 20 ul of 1500 x H19 dye, 450 ul of 10 x ATP, 3000 ul of 10 x H19 dilution buffer and 50 ul 100 x E.coli gyrase.

96-Well E. coli gyrase DNA Decatenation Assay Kit Plus (enzyme included)

T2DD-96KE 96 assays
EUR 591.41
Description: This product includes the assay buffer, concatenated DNA, E. coli gyrase, ATP, fluorescence dye, rinse buffer and a TDD filter plate for 96 assays of E. coli gyrase DNA decatenation reactions.

EpiQuik General Protein-DNA Binding Assay Kit (Colorimetric) 

P-2004
  • EUR 736.86
  • EUR 486.20
  • 96 Assays
  • 96 Assays

EpiQuik General Protein-DNA Binding Assay Kit (Fluorometric) 

P-2005
  • EUR 754.26
  • EUR 490.60
  • 96 Assays
  • 96 Assays

96-Well S. aureus gyrase DNA Decatenation Assay Kit Plus (enzyme included)

T2DD-96KS 96 assays
EUR 681.29
Description: This product includes 600 ul of 10 x assay buffer, 500 ul of 10 x concatenated DNA, 120 ul of 10 mM ATP, 100 ul of 50 x S. aureus gyrase, 600 ul of Stop solution (0.4 M EDTA), 500 ul of 10 x fluorescence dye, 2 ml of 10 x rinse buffer, one V-bottom plate, a TDD filter plate and one black 96-well plates for 96 assays of DNA decatenation reactions.

E. coli NAD+-dependent DNA ligase assay kit Plus (E. coli ligase included)

NLA100KE 100 assays
EUR 444.91
Description: This product includes 800 ul of 10 x buffer, 44 ul of 100x DNA substrate, 44 ul of 100 x NAD+, 21 ml of Reagent T, 10 ul of 500 x E. coli ligase and 220 ul of 10 x fluorescence dye for 100 assays.

96-well S. aureus Topo IV DNA Cleavage Assay Kit Plus (enzyme included)

T4C96KS 96 assays
EUR 777.46
Description: This product includes all the components in TDC96K plus 26 ul of 100 x S. aureus Topo IV.

96-Well E. coli Topo IV DNA Decatenation Assay Kit Plus (enzyme included)

EDD96KE 96 assays
EUR 591.41
Description: This product includes 600 ul of 10 x assay buffer, 500 ul of 10 x concatenated DNA, 110 ul of 10 mM ATP, 8 ul of 1000 x E. coli topo IV, 600 ul of 0.4 M EDTA, 260 ul of 20 x fluorescence dye, 2 ml of 10 x rinse buffer, one V-bottom plate, a TDD filter plate and one black 96-well plates for 96 assays of DNA decatenation reactions.

96-Well E. coli Topo I DNA Decatenation Assay Kit Plus (enzyme included)

T1DD-96KE 96 assays
EUR 591.41
Description: This product includes the assay buffer, concatenated DNA, E. coli topo I, fluorescence dye, rinse buffer and a TDD filter plate for 96 assays of E. coli topo I DNA decatenation reactions.

E. coli DNA Topoisomerase II (Gyrase) Assay Kit Plus (E. coli gyrase included)

DSA020KE 20 assays
EUR 221.78
Description: This product includes160 ul of 10 x Buffer T2, 84 ul of 10 x relaxed DNA, 6 ul of 1500 x H19 dye, 90 ul of 10 x ATP and 550 ul of 10 x H19 dilution buffer. It is for 20 assays in 96-well plate format. E. coli gyrase is not included.

XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)

30007 1KIT
EUR 283.2
Description: Minimum order quantity: 1 unit of 1KIT

96-Well S. aureus Topo IV DNA Decatenation Assay Kit Plus (enzyme included)

SDD96KE 96 assays
EUR 681.29
Description: This product includes 600 ul of 10 x assay buffer, 500 ul of 10 x concatenated DNA, 110 ul of 10 mM ATP, 8 ul of 1000 x S. aureus topo IV, 600 ul of 0.4 M EDTA, 260 ul of 20 x fluorescence dye, 2 ml of 10 x rinse buffer, one V-bottom plate, a TDD filter plate and one black 96-well plates for 96 assays of DNA decatenation reactions.

96-Well S. pneumoniae Topo IV DNA Decatenation Assay Kit Plus (enzyme included)

NDD96KE 96 assays
EUR 681.29
Description: This product includes 600 ul of 10 x assay buffer, 500 ul of 10 x concatenated DNA, 110 ul of 10 mM ATP, 8 ul of 1000 x S. pneumoniae topo IV, 600 ul of 0.4 M EDTA, 260 ul of 20 x fluorescence dye, 2 ml of 10 x rinse buffer, one V-bottom plate, a TDD filter plate and one black 96-well plates for 96 assays of DNA decatenation reactions.

96-Well P. aeruginosa Topo IV DNA Decatenation Assay Kit Plus (enzyme included)

PDD96KE 96 assays
EUR 681.29
Description: This product includes 600 ul of 10 x assay buffer, 500 ul of 10 x concatenated DNA, 110 ul of 10 mM ATP, 8 ul of 1000 x P. aeruginosa topo IV, 600 ul of 0.4 M EDTA, 260 ul of 20 x fluorescence dye, 2 ml of 10 x rinse buffer, one V-bottom plate, a TDD filter plate and one black 96-well plates for 96 assays of DNA decatenation reactions.

ADA Assay Kit

abx098403-Hitachi7060R190ml2R290ml1 Hitachi 7060; R1: 90ml×2 R2: 90ml×1
EUR 886.8

ADA Assay Kit

abx098403-Hitachi7170R140ml4R220ml4 Hitachi 7170; R1: 40ml×4 R2: 20ml×4
EUR 961.2

ADA Assay Kit

abx098403-Hitachi7170R160ml4R260ml2 Hitachi 7170; R1: 60ml×4 R2: 60ml×2
EUR 1093.2

ADA Assay Kit

abx098403-Toshiba40R150ml4R250ml2 Toshiba 40; R1: 50ml×4 R2: 50ml×2
EUR 943.2

RET Assay Kit

79566 96 rxns.
EUR 535
Description: RET is a receptor kinase for GDNF (glial cell-line derived neurotrophic factor) family ligands (GFLs). Activation of wild-type RET is important in several cancers where it contributes to tumor progression through various mechanisms. In addition, it has been shown that activating mutation as well as RET rearrangement that leads constitutively active protein plays a significant role in various cancer types. Importantly, small molecule inhibitors of RET have been clinically proved as a promising therapeutic reagent in medullary thyroid cancer and are being evaluated for other types of cancers related to RET overexpression or mutation. The RET Assay Kit is designed to measure RET activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The RET Assay Kit comes in a convenient 96-well format, with enough purified recombinant RET enzyme, RET substrate peptide (IRF-1Rtide), ATP and kinase assay buffer for 100 enzyme reactions.

BTK Assay Kit

79568 96 rxns.
EUR 560
Description: Bruton's tyrosine kinase or BTK, is an enzyme that plays a role in the functionality and maturation of B cells. The BTK pathway has implications for a number of autoimmune disorders including isolated growth hormone deficiency type III and rheumatoid arthritis. The BTK Assay Kit is designed to measure BTK activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The BTK Assay Kit comes in a convenient 96-well format, with enough purified recombinant BTK enzyme, PolyGluTyr peptide, ATP, and kinase assay buffer for 100 enzyme reactions.

SYK Assay Kit

79671 96 rxns.
EUR 525
Description: SYK of the nonreceptor tyrosine kinases plays a role in autoimmune diseases like Epstein Barr virus and hematopoietic malignancies. The SYK Assay Kit is designed to measure SYK activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

SRC Assay Kit

79680 96 rxns.
EUR 535
Description: SRC is a member of the nonreceptor tyrosine kinases that plays a role in many cellular functions, including cell adhesion, growth, and differentiation. SRC has been implicated in diseases such as chronic kidney disease and metastatic bone disease. The SRC Assay Kit is designed to measure SRC activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The SRC Assay Kit comes in a convenient 96-well format, with enough purified recombinant SRC enzyme, Protein Tyrosine Kinase Substrate (Poly-Glu,Tyr 4:1), ATP, and kinase assay buffer for 100 enzyme reactions.

LCK Assay Kit

79794 96 rxns.
EUR 535
Description: The LCK Assay Kit is designed to measure LCK activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

POP Assay Kit

80106 96 rxns.
EUR 685
Description: The Fluorogenic Prolyl OligoPeptidase (POP)_x000D_ Assay Kit is a complete assay system designed to measure activity of the purified POP_x000D_ enzyme. The Fluorogenic POP Activity Kit eliminates the dealing with radioactive_x000D_ materials and chromatography in traditional assays. Purified human recombinant POP is_x000D_ included in the kit as a positive control. Using this kit, only one simple step, in which the_x000D_ fluorometric substrate is incubated with purified POP, is needed to analyze the POP_x000D_activity level. The resulting fluorescent product can then be easily measured with a_x000D_ microtiter-plate fluorimeter.

FAP Assay Kit

80210 96 rxns.
EUR 1175
Description: The Fluorogenic FAP Assay Kit is designed to measure FAP activity using purified_x000D_FAP for screening and profiling applications. _x000D_The key to the Fluorogenic FAP Assay Kit is the fluorogenic substrate. Using this kit,_x000D_only one simple step on a microtiter plate is required for FAP reactions. The DPP_x000D_fluorometric substrate is incubated with a sample containing FAP enzyme to produce a_x000D_fluorophore that can then be measured using a fluorescence reader.

FYN Assay Kit

78003 96 rxns.
EUR 535
Description: The FYN Assay Kit is designed to measure FYN activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

ADA Assay Kit

abx090675-100tests 100 tests
EUR 284.4

HAT Assay Kit

55R-1373 100 assays
EUR 888
Description: Assay Kit for detection of HAT in the research laboratory

SOD Assay Kit

55R-1374 100 assays
EUR 722.4
Description: Assay Kit for detection of SOD in the research laboratory

ATP Assay Kit

55R-1380 100 assays
EUR 970.8
Description: Assay Kit for detection of ATP in the research laboratory

ADP Assay Kit

55R-1381 100 assays
EUR 970.8
Description: Assay Kit for detection of ADP in the research laboratory

FAD Assay Kit

55R-1382 100 assays
EUR 878.4
Description: Assay Kit for detection of FAD in the research laboratory

PEP Assay Kit

55R-1384 100 assays
EUR 1051.2
Description: Assay Kit for detection of PEP in the research laboratory

JNK Assay Kit

55R-1407 40 assays
EUR 1041.6
Description: Assay Kit for detection of JNK in the research laboratory

JNK Assay Kit

55R-1408 40 assays
EUR 1174.8
Description: Assay Kit for detection of JNK in the research laboratory

Akt Assay Kit

55R-1409 40 assays
EUR 1174.8
Description: Assay Kit for detection of Akt in the research laboratory

MDA Assay Kit

55R-1512 100 assays
EUR 970.8
Description: Assay Kit for detection of MDA in the research laboratory

PAH Assay Kit

55R-1547 100 assays
EUR 888
Description: Assay Kit for detection of PAH in the research laboratory

ATP Assay Kit

Z5030041 100 assays
EUR 636

Iron Assay Kit

abx098439-Hitachi7020R140ml1R210ml1 Hitachi 7020; R1:40ml×1 R2:10ml×1
EUR 247.2

Iron Assay Kit

abx098439-Hitachi7170R140ml1R210ml1 Hitachi 7170; R1:40ml×1 R2:10ml×1
EUR 247.2

Iron Assay Kit

abx098439-Hitachi7170R160ml1R215ml1 Hitachi 7170; R1:60ml×1 R2:15ml×1
EUR 266.4

Iron Assay Kit

abx098439-Toshiba40R140ml1R210ml1 Toshiba 40; R1:40ml×1 R2:10ml×1
EUR 247.2

NGAL Assay Kit

abx098449-Hitachi7020R140ml1R210ml1 Hitachi 7020; R1: 40ml×1 R2: 10ml×1
EUR 1130.4

NGAL Assay Kit

abx098449-Hitachi7170R120ml1R25ml1 Hitachi 7170; R1: 20ml×1 R2: 5ml×1
EUR 679.2

NGAL Assay Kit

abx098449-Hitachi7170R140ml1R210ml1 Hitachi 7170; R1: 40ml×1 R2: 10ml×1
EUR 1130.4

NGAL Assay Kit

abx098449-Toshiba120R140ml1R210ml1 Toshiba 120; R1: 40ml×1 R2: 10ml×1
EUR 1130.4

NGAL Assay Kit

abx098449-Toshiba40R140ml1R210ml1 Toshiba 40; R1: 40ml×1 R2: 10ml×1
EUR 1130.4

Urea Assay Kit

abx098464-Hitachi7020R150ml4R250ml1 Hitachi 7020; R1: 50ml×4 R2: 50ml×1
EUR 266.4

Urea Assay Kit

abx098464-Hitachi7060R190ml2R245ml1 Hitachi 7060; R1: 90ml×2 R2: 45ml×1
EUR 266.4

Urea Assay Kit

abx098464-Toshiba120R140ml4R240ml1 Toshiba 120; R1: 40ml×4 R2: 40ml×1
EUR 266.4

AMBP Assay Kit

abx098467-Hitachi7060R145ml1R215ml1 Hitachi 7060; R1: 45ml×1 R2: 15ml×1
EUR 585.6

AMBP Assay Kit

abx098467-Hitachi7060R190ml2R230ml2 Hitachi 7060; R1: 90ml×2 R2: 30ml×2
EUR 622.8

AMBP Assay Kit

abx098467-Hitachi7170R145ml1R215ml1 Hitachi 7170; R1: 45ml×1 R2: 15ml×1
EUR 585.6

AMBP Assay Kit

abx098467-Toshiba40R145ml1R215ml1 Toshiba 40; R1: 45ml×1 R2: 15ml×1
EUR 585.6

TrkA Assay Kit

79548 96 rxns.
EUR 535
Description: The tropomyosin receptor kinases (TRK) are a family of tyrosine receptor kinases, which include TrkA, TrkB and TrkC. TrkA is activated by binding to nerve growth factor (NGF), resulting in activation of cell proliferation through the RAS/MAPK/ERK and PLCγ/PI3K pathways. Constitutive activation of TrkA is associated with colorectal cancer, suggesting TrkA inhibitors may have potential therapeutic value. The TrkA Assay Kit is designed to measure TrkA activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The TrkA Assay Kit comes in a convenient 96-well format, with enough purified recombinant TrkA enzyme, TrkA substrate, ATP and kinase assay buffer for 100 enzyme reactions.

CDK1 Assay Kit

79597 96 rxns.
EUR 535
Description: Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle. CDKs are active only when bound to their regulator proteins, cyclins. CDK activity is tightly controlled for successful cell division. Since abnormal cell division represents cancer pathology, controlling CDK activity has been shown as a promising therapeutic strategy. In particular, CDK1 plays an important role in mitotic progression. The CDK1 Assay Kit is designed to measure CDK1/CyclinB1 activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent.

CDK2 Assay Kit

79599 96 rxns.
EUR 535
Description: Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle. CDKs are active only when bound to their regulator proteins, cyclins. CDK activity is tightly controlled for successful cell division. Since abnormal cell division represents cancer pathology, controlling CDK activity has been shown as a promising therapeutic strategy. In particular, CDK2 plays an important role in DNA replication. The CDK2 Assay Kit is designed to measure CDK2/CyclinA2 activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent.

CDK5 Assay Kit

79600 96 rxns.
EUR 535
Description: CDK5 is an unconventional member of the CDK family. It is expressed in post-mitotic neurons, and its activity is regulated by neuron-specific activators p35/p25 and p39 rather than the cyclins. It has been suggested that CDK5 plays several roles in the nervous system, including Tau aggregation and tangle formation. The CDK5 Assay Kit is designed to measure CDK5 activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent.

CDK7 Assay Kit

79603 96 rxns.
EUR 535
Description: Cyclin-dependent kinase 7 (CDK7) assembled with Cyclin H and MAT1 comprises an important sub-component of the transcription factor TFIIH. It is known to have dual roles, which include transcription regulation via phosphorylating the C-terminal domain (CTD) of RNA polymerase II as well as controlling cell cycle progression as a CDK activating kinase (CAK). The CDK7 Assay Kit is designed to measure CDK7/Cyclin H/MAT1 activity for screening and profiling applications, using ADP-Glo® as a detection reagent.

CDK9 Assay Kit

79628 96 rxns.
EUR 575
Description: Cyclin-dependent kinase 9 (CDK9) is the catalytic subunit of the positive transcription elongation factor b (P-TEFb), which phosphorylates the C-terminal domain of RNA polymerase II, a key player in the production of mature RNA. The CDK9 Assay Kit is designed to measure CDK9/CyclinT activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent. The CDK9 Assay Kit comes in a convenient 96-well format, with enough purified recombinant CDK9/CyclinT enzyme, CDK substrate peptide 2, ATP and kinase assay buffer for 100 enzyme reactions.

CDK4 Assay Kit

79674 96 rxns.
EUR 550
Description: Cyclin-dependent kinase 4 (CDK4) assembles with the "D" type of Cyclins, e.g. cyclins D1, D2, and D3, and play a pivotal role in the cell cycle entering the S phase. Dysregulation of the activity of CDK4 is related to many different cancers, indicating CDK4 inhibitors as promising anticancer treatments. In fact, multiple CDK4 inhibitors, including Palbociclib, were approved by the FDA recently. The CDK4 Assay Kit is designed to measure CDK4/CyclinD3 activity for screening and profiling applications, using Kinase-Glo® Max as a detection reagent.

YES1 Assay Kit

79681 96 rxns.
EUR 535
Description: Proto-oncogene tyrosine-protein kinase YES1 has been implicated in regulation of cell growth and survival, apoptosis, cell-cell adhesion, and differentiation. It has been identified as a potential target in basal-like breast cancers. The YES1 Assay Kit is designed to measure YES1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The YES1 Assay Kit comes in a convenient 96-well format, with enough purified recombinant YES1 enzyme, Protein Tyrosine Kinase Substrate (Poly-Glu,Tyr 4:1), ATP, and kinase assay buffer for 100 enzyme reactions.

HPK1 Assay Kit

79775 96 rxns.
EUR 560
Description: The HPK1 Assay Kit is designed to measure HPK1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

cKIT Assay Kit

79815 96 rxns.
EUR 535
Description: The cKIT Assay Kit is designed to measure cKIT activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.

TBK1 Assay Kit

79871 96 rxns.
EUR 510
Description: The TBK1 Assay Kit is designed to measure TBK1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
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